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染色质修饰蛋白颁贬惭笔6抗体注意事项；This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Function: Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. In the ESCRT-III complex, it probably serves as an acceptor for the ESCRT-II complex on endosomal membranes.
半乳糖转移酶7亚基β1,4抗体免 疫 原；KLH conjugated synthetic peptide derived from human B4GALT7: 201-300/327
染色质修饰蛋白颁贬惭笔7抗体注意事项；This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Function: CHMP7 plays a role in the endosomal sorting pathway and is a component of the ESCRT III complex.
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