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半乳糖转移酶7亚基β1,4抗体
产物名称 | 英文名称 | 货号 |
半乳糖转移酶7亚基β1,4抗体 | B4GALT7 | GOY-01K1006 |
商品属性:
英文名称: B4GALT7
中文名:半乳糖转移酶7亚基β1,4抗体
别 名;B4GAL T7; Beta
1,4 galactosyltransferase 7; Beta 1,4 GalTase 7; Beta4Gal T7; UDP Gal:beta
GlcNAc beta 1,4 galactosyltransferase 7; XGALT 1; XGALT1; XGPT1; Xylosylprotein
beta 1,4 galactosyltransferase, polypeptide 7; B4GT7_HUMAN.
研究领域;细胞生物 免疫学 信号转导 细胞周期蛋白 细胞分化 细胞骨架 细胞外基质
抗体来源;Rabbit
克隆类型;Polyclonal
交叉反应;(predicted:
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
产物应用;WB=1:500-2000
ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复)
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理论分子量;37kDa
细胞定位;细胞浆 细胞膜
性 状;Liquid
浓 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human B4GALT7: 201-300/327
亚 型;IgG
纯化方法;affinity
purified by Protein A
缓 冲 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事项;This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
产物介绍:
β-1,4-galactosyltransferases (β-1,4-Gal-T) are type II membrane-bound glycoproteins that are
substrate-specific and function to transfer galactose in a β-1,4 linkage to an acceptor sugar. There are seven members of the β-1,4-Gal-T family, all of which are directed to the golgi
apparatus through a hydrophobic sequence at the N-terminus. β-1,4-Gal-T7, also known as B4GALT7 or XGALT1, is a 327 amino acid
single-pass type II membrane protein that is expressed at high levels in
heart, pancreas and liver. β-1,4-Gal-T7 uses
manganese to catalyze the UDP-dependent biosynthesis of glycosphingolipids.
The gene encoding β-1,4-Gal-T7 is mutated in
Ehlers-Danlos syndrome progeroid type (EDSP), a variant form of Ehlers-Danlos
syndrome characterized by progeroid facies, mild mental retardation, short
stature, skin hyperextensibility, moderate skin fragility, joint
hypermobility principally in digits.β-1,4-galactosyltransferases
(β-1,4-Gal-T) are type II membrane-bound
glycoproteins that are substrate-specific and function to transfer galactose
in a ∫-1,4 linkage to an acceptor sugar. There are
seven members of the β-1,4-Gal-T family, all of which
are directed to the golgi apparatus through a hydrophobic sequence at the
N-terminus. β-1,4-Gal-T7, also known as B4GALT7 or
XGALT1, is a 327 amino acid single-pass type II membrane protein that is
expressed at high levels in heart, pancreas and liver. β-1,4-Gal-T7 uses manganese to catalyze the UDP-dependent
biosynthesis of glycosphingolipids. The gene encoding β-1,4-Gal-T7 is mutated in Ehlers-Danlos syndrome progeroid type
(EDSP), a variant form of Ehlers-Danlos syndrome characterized by progeroid
facies, mild mental retardation, short stature, skin hyperextensibility,
moderate skin fragility, joint hypermobility principally in
digits.-1,4-galactosyltransferases (β-1,4-Gal-T) are
type II membrane-bound glycoproteins that are substrate-specific and function
to transfer galactose in a ∫-1,4 linkage to an
acceptor sugar. There are seven members of the β-1,4-Gal-T
family, all of which are directed to the golgi apparatus through a
hydrophobic sequence at the N-terminus. β-1,4-Gal-T7,
also known as B4GALT7 or XGALT1, is a 327 amino acid single-pass type II
membrane protein that is expressed at high levels in heart, pancreas and
liver. β-1,4-Gal-T7 uses manganese to catalyze the
UDP-dependent biosynthesis of glycosphingolipids. The gene encoding β-1,4-Gal-T7 is mutated in Ehlers-Danlos syndrome progeroid type
(EDSP), a variant form of Ehlers-Danlos syndrome characterized by progeroid
facies, mild mental retardation, short stature, skin hyperextensibility,
moderate skin fragility, joint hypermobility principally in digits. Required for the biosynthesis of the
tetrasaccharide linkage region of proteoglycans, especially for small
proteoglycans in skin fibroblasts. |
多克隆抗体制备:
我公司合成抗原,保证阳性血清和抗体贰尝滨厂础效价达到1:32000,由蛋白抗原制备的多抗,保证奥叠检测结果是阳性。技术服务实行分步报价,按节点收费,为客户节约成本。
鼠单克隆抗体制备:
客户可根据项目实际需求情况灵活选择进行,我公司将为您的项目提供专业的建议。在制备过程中,与客户互动验证,确保最终制备的抗体贰尝滨厂础阳性血清检测达到合同要求的同时,也能满足客户抗体最终应用验证需求。技术服务实行分步报价,按节点收费,为客户节约成本。
重组抗体表达服务:
重组抗体技术使制备人源化抗体和人源抗体成为可能,而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。我公司已搭建好的抗体测序、重组抗体表达等先进平台,能为客户提供各种类型的重组抗体表达服务,包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达,抗体人源化改造及表达等服务。
单项免疫学及检测服务:
我公司也为客户提供单项免疫学和检测服务,如动物免疫、动物饲养、抗体修饰服务(如贵滨罢颁,贬搁笔等的标记)、以及贰尝滨厂础,奥叠,滨贬颁,顿叠等检测服务。
抗体定制服务:
已注册商标,主要用于抗体药物发现和开发,是我公司针对有特定应用要求和各种模型测试的客户量身定制的专业服务,主要面向工业客户。
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