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ATP6V1B2蛋白抗体
产物名称 | 英文名称 | 货号 |
ATP6V1B2蛋白抗体 | ATP6V1B2 | GOY-01K4404 |
商品属性:
英文名称: ATP6V1B2
中文名:ATP6V1B2蛋白抗体
别 名;V-ATPase B2;
ATP6B1B2; ATP6B2; ATP6V1 B2; ATP6V1B 2; ATP6V1B2; ATPase H+ transporting
lysosomal 56/58kDa V1 subunit B isoform 2; ATPase H+ transporting lysosomal
56/58kDa V1 subunit B2; ATPase H+ transporting, lysosomal (vacuolar proton
pump) beta polypeptide 56/58kD isoform 2; ATPase, H+ transporting, lysosomal V1
subunit B2; brain isoform; Endomembrane proton pump 58 kDa subunit; H+
transporting two sector ATPase; HO 57; HO57; V ATPase B2 subunit; V ATPase
subunit B 2; V type proton ATPase subunit B, brain isoform; V-ATPase subunit B
2; V-type proton ATPase subunit B; Vacuolar ATP synthase subunit B brain
isoform; Vacuolar H+ ATPase 56,000 subunit; Vacuolar H+ ATPase 56000 subunit;
Vacuolar H+ATPase B2; Vacuolar proton pump subunit B 2; VAT B2; VATB 2; VATB;
VATB2; VATB2_HUMAN; Vma 2; Vma2; VPP 3; VPP3.
研究领域;肿瘤 细胞生物 免疫学 神经生物学 信号转导 新陈代谢 表观遗传学
抗体来源;Rabbit
克隆类型;Polyclonal
交叉反应;(predicted:
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
产物应用;WB=1:500-2000
ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理论分子量;56kDa
细胞定位;细胞膜
性 状;Liquid
浓 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human ATP6V1B2: 51-150/511
亚 型;IgG
纯化方法;affinity
purified by Protein A
缓 冲 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件;Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事项;This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
产物介绍:
Vacuolar-type H+-ATPase (V-ATPase) is a
multisubunit enzyme responsible for acidification of eukaryotic intracellular
organelles. V-ATPases pump protons against an electrochemical gradient, while
F-ATPases reverse the process, thereby synthesizing ATP. A peripheral V1
domain, which is responsible for ATP hydrolysis, and a integral V0 domain,
which is responsible for proton translocation, compose V-ATPase. Nine
subunits (A–H) make up the V1 domain and
five subunits (a, d, c, c' and c") make up the V0 domain. Like F-ATPase,
V-ATPase most likely operates through a rotary mechanism. The V-ATPase V1 B
subunit exists as two isoforms. In the inner ear, the V-ATPase B1 isoform
functions in proton secretion and is required to maintain proper endolymph pH
and normal auditory function. The gene encoding the human V-ATPase B1 isoform
maps to chromosome 2cen-q13. Mutations in this gene cause distal renal tubular
acidosis associated with sensorineural deafness. The V-ATPase B2 isoform is
expressed in kidney and is the only B isoform expressed in osteoclasts. The
gene encoding the human V-ATPase B2 isoform maps to chromosome 8p22-p21. Function: Non-catalytic subunit of the peripheral V1 complex
of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of
intracellular compartments in eukaryotic cells. |
多克隆抗体制备:
我公司合成抗原,保证阳性血清和抗体贰尝滨厂础效价达到1:32000,由蛋白抗原制备的多抗,保证奥叠检测结果是阳性。技术服务实行分步报价,按节点收费,为客户节约成本。
鼠单克隆抗体制备:
客户可根据项目实际需求情况灵活选择进行,我公司将为您的项目提供专业的建议。在制备过程中,与客户互动验证,确保最终制备的抗体贰尝滨厂础阳性血清检测达到合同要求的同时,也能满足客户抗体最终应用验证需求。技术服务实行分步报价,按节点收费,为客户节约成本。
重组抗体表达服务:
重组抗体技术使制备人源化抗体和人源抗体成为可能,而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。我公司已搭建好的抗体测序、重组抗体表达等先进平台,能为客户提供各种类型的重组抗体表达服务,包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达,抗体人源化改造及表达等服务。
单项免疫学及检测服务:
我公司也为客户提供单项免疫学和检测服务,如动物免疫、动物饲养、抗体修饰服务(如贵滨罢颁,贬搁笔等的标记)、以及贰尝滨厂础,奥叠,滨贬颁,顿叠等检测服务。
抗体定制服务:
已注册商标,主要用于抗体药物发现和开发,是我公司针对有特定应用要求和各种模型测试的客户量身定制的专业服务,主要面向工业客户。
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