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ATP结合蛋白家族7抗体
产物名称 | 英文名称 | 货号 |
ATP结合蛋白家族7抗体 | ABCB7 | GOY-01K1137 |
商品属性:
英文名称: ABCB7
中文名:ATP结合蛋白家族7抗体
别 名;ABC transporter 7
protein; ABC7; Abcb7; ABCB7_HUMAN; ASAT; Atm1p; ATP binding cassette 7; ATP
binding cassette sub family B (MDR/TAP) member 7; ATP binding cassette sub
family B member 7; ATP binding cassette sub family B member 7 mitochondrial;
ATP binding cassette transporter 7; ATP-binding cassette sub-family B member 7;
ATP-binding cassette transporter 7; EST140535; MDR7; mitochondrial; Multidrug
resistance protein 7; P-glycoprotein 7; PGP7.
研究领域;细胞生物 信号转导 干细胞 新陈代谢
抗体来源;Rabbit
克隆类型;Polyclonal
交叉反应;(predicted:
Human, Mouse, Rat, Dog, Pig, Rabbit, Sheep, )
产物应用;ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理论分子量;83kDa
细胞定位;细胞浆 细胞膜
性 状;Liquid
浓 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from Human ABCB7: 201-300/752
亚 型;IgG
纯化方法;affinity
purified by Protein A
缓 冲 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件;Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事项;This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
产物介绍:
The peroxisomal membrane contains several
ATP-binding cassette (ABC) transporters, ABCD1–4 that are known to be present in the human peroxisome membrane
(1). All four proteins are ABC half-transporters, which dimerize to form an
active transporter (1). A mutation in the ABCD1 causes X-linked
adrenoleukodystrophy (X-ALD), a peroxisomal disorder which affects lipid
storage (2,3). ABCD2 in mouse, is expressed at high levels in the brain and
adrenal organs, which are adversely affected in X-ALD (4). The peroxisomal
membrane comprises 2 quantitatively major proteins, PMP22 and ABCD3 (5).
ABCD3 is associated with irregularly shaped vesicles which may be defective
peroxisomes or peroxisome precursors (5). ABCD4 localizes to peroxisomes (1).
The genes which encode ABCD1–4 map to human
chromosome Xq28, 12q11-q12, 1p22-p21 and 14q24.3, respectively (3,6–8). ABCB7 is a half-transporter involved in the transport of heme
from the mitochondria to the cytosol and maps to human chromosome
Xq13.1-q13.3 (9). Function: Could be involved in the transport of heme from
the mitochondria to the cytosol. Plays a central role in the maturation of
cytosolic iron-sulfur (Fe/S) cluster-containing proteins. |
多克隆抗体制备:
我公司合成抗原,保证阳性血清和抗体贰尝滨厂础效价达到1:32000,由蛋白抗原制备的多抗,保证奥叠检测结果是阳性。技术服务实行分步报价,按节点收费,为客户节约成本。
鼠单克隆抗体制备:
客户可根据项目实际需求情况灵活选择进行,我公司将为您的项目提供专业的建议。在制备过程中,与客户互动验证,确保最终制备的抗体贰尝滨厂础阳性血清检测达到合同要求的同时,也能满足客户抗体最终应用验证需求。技术服务实行分步报价,按节点收费,为客户节约成本。
重组抗体表达服务:
重组抗体技术使制备人源化抗体和人源抗体成为可能,而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。我公司已搭建好的抗体测序、重组抗体表达等先进平台,能为客户提供各种类型的重组抗体表达服务,包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达,抗体人源化改造及表达等服务。
单项免疫学及检测服务:
我公司也为客户提供单项免疫学和检测服务,如动物免疫、动物饲养、抗体修饰服务(如贵滨罢颁,贬搁笔等的标记)、以及贰尝滨厂础,奥叠,滨贬颁,顿叠等检测服务。
抗体定制服务:
已注册商标,主要用于抗体药物发现和开发,是我公司针对有特定应用要求和各种模型测试的客户量身定制的专业服务,主要面向工业客户。
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