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钙激活钾通道蛋白β1抗体
产物名称 | 英文名称 | 货号 |
钙激活钾通道蛋白β1抗体 | Maxi Potassium channel beta | GOY-01K5725 |
商品属性:
英文名称: Maxi Potassium channel beta
中文名:钙激活钾通道蛋白β1抗体
英文别名英文别名 Human, Mouse, Rat, Dog, Pig, Cow, Horse,
Rabbit, Sheep
标记 Unconjugated
抗体来源 Rabbit
抗体类型 Polyclonal
免疫原 KLH conjugated synthetic peptide derived from
human Maxi Potassium channel beta
蛋白细胞定位 细胞膜
纯化方法 affinity purified by Protein A
亚型 IgG
性状 Liquid
浓度 1mg/ml
储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03%
Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store
at -20 °C for one year. Avoid repeated freeze/thaw
cycles.
产物介绍:
Potassium channels are a group of ubiquitously
expressed proteins that serve numerous functions in excitable and
non-excitable cells. One class of integral membrane potassium channels is the
large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+
differs from most other potassium channels in that its activation is
controlled by both increases in intracellular calcium and by membrane
depolarization. Maxi K+ dual activation is possible because of its structure.
The core of the channel, which is similar to other potassium channels, is a
Maxi K+ alpha homotetramer that contains both a voltage sensor and an
intracellular calcium binding domain. In vascular smooth muscle, an auxiliary
beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its
effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the
concentration of calcium required to keep the pore open. Maxi K+ beta is the
target for possible therapeutics because of its role in blood flow and blood
pressure regulation. |
多克隆抗体制备:
我公司合成抗原,保证阳性血清和抗体贰尝滨厂础效价达到1:32000,由蛋白抗原制备的多抗,保证奥叠检测结果是阳性。技术服务实行分步报价,按节点收费,为客户节约成本。
鼠单克隆抗体制备:
客户可根据项目实际需求情况灵活选择进行,我公司将为您的项目提供专业的建议。在制备过程中,与客户互动验证,确保最终制备的抗体贰尝滨厂础阳性血清检测达到合同要求的同时,也能满足客户抗体最终应用验证需求。技术服务实行分步报价,按节点收费,为客户节约成本。
重组抗体表达服务:
重组抗体技术使制备人源化抗体和人源抗体成为可能,而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。我公司已搭建好的抗体测序、重组抗体表达等先进平台,能为客户提供各种类型的重组抗体表达服务,包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达,抗体人源化改造及表达等服务。
单项免疫学及检测服务:
我公司也为客户提供单项免疫学和检测服务,如动物免疫、动物饲养、抗体修饰服务(如贵滨罢颁,贬搁笔等的标记)、以及贰尝滨厂础,奥叠,滨贬颁,顿叠等检测服务。
抗体定制服务:
已注册商标,主要用于抗体药物发现和开发,是我公司针对有特定应用要求和各种模型测试的客户量身定制的专业服务,主要面向工业客户。
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