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甲状腺激素受体相关蛋白3抗体
产物名称 | 英文名称 | 货号 |
甲状腺激素受体相关蛋白3抗体 | THRAP3/TR150 | GOY-01K5233 |
商品属性:
英文名称: THRAP3/TR150
中文名:甲状腺激素受体相关蛋白3抗体
英文别名 FLJ22082; THRAP3; Thyroid hormone receptor
associated protein 3; Thyroid hormone receptor-associated protein 3; Thyroid
hormone receptor-associated protein complex 150 kDa component; Thyroid hormone
receptor-associated protein complex; TR150_HUMAN; Trap150.
交叉反应 Human, Mouse, Rat, Pig, Cow, Horse, Rabbit,
Sheep
标记 Unconjugated
抗体来源 Rabbit
抗体类型 Polyclonal
免疫原 KLH conjugated synthetic peptide derived from
human THRAP3/TR150
蛋白细胞定位 细胞核
纯化方法 affinity purified by Protein A
亚型 IgG
性状 Liquid
浓度 1mg/ml
储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03%
Proclin300 and 50% Glycerol.
保存条件 Shipped at 4℃. Store
at -20 °C for one year. Avoid repeated freeze/thaw
cycles.
产物介绍:
In mammalian cells, transcription is regulated in
part by high molecular weight coactivating complexes that mediate signaling
between transcriptional activators and initiation factors. These complexes
include the thyroid hormone receptor-associated protein (TRAP) complex, which
interacts with thyroid receptors (TR), vitamin D receptors and other steroid
receptors to facilitate hormone induced transcriptional activation. The TRAP
complex consists of numerous proteins ranging in size including TRAP95,
TRAP100, TRAP150, TRAP220 and TRAP230, that are characterized by the presence
of a nuclear receptor recognition motif which mediates the ligand-dependent
binding of TRAP proteins to the nuclear receptors. TRAP220 and TRAP100 are
widely expressed and most abundantly detected in skeletal muscle, heart and
placenta. TRAP95, TRAP150 and TRAP230 facilitate TR induced transcription by
associating with an additional transcriptional coactivating complex SMCC (SRB
and MED protein cofactor complex), which consists of various subunits that
share homology with several components of the yeast transcriptional mediator
complexes. |
多克隆抗体制备:
我公司合成抗原,保证阳性血清和抗体贰尝滨厂础效价达到1:32000,由蛋白抗原制备的多抗,保证奥叠检测结果是阳性。技术服务实行分步报价,按节点收费,为客户节约成本。
鼠单克隆抗体制备:
客户可根据项目实际需求情况灵活选择进行,我公司将为您的项目提供专业的建议。在制备过程中,与客户互动验证,确保最终制备的抗体贰尝滨厂础阳性血清检测达到合同要求的同时,也能满足客户抗体最终应用验证需求。技术服务实行分步报价,按节点收费,为客户节约成本。
重组抗体表达服务:
重组抗体技术使制备人源化抗体和人源抗体成为可能,而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。我公司已搭建好的抗体测序、重组抗体表达等先进平台,能为客户提供各种类型的重组抗体表达服务,包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达,抗体人源化改造及表达等服务。
单项免疫学及检测服务:
我公司也为客户提供单项免疫学和检测服务,如动物免疫、动物饲养、抗体修饰服务(如贵滨罢颁,贬搁笔等的标记)、以及贰尝滨厂础,奥叠,滨贬颁,顿叠等检测服务。
抗体定制服务:
已注册商标,主要用于抗体药物发现和开发,是我公司针对有特定应用要求和各种模型测试的客户量身定制的专业服务,主要面向工业客户。
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