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5-氨基乙酰丙酸合酶1抗体
产物名称 | 英文名称 | 货号 |
5-氨基乙酰丙酸合酶1抗体 | ALAS-E | GOY-01K4173 |
商品属性:
英文名称: ALAS-E
中文名:5-氨基乙酰丙酸合酶1抗体
英文别名 :5-aminolevulinate
synthase, erythroid-specific, mitochondrial; 5-aminolevulinic acid synthase;
ALAS E; ALASE; ANH1; Delta aminolevulinate synthase; XLSA; 5 aminolevulinic
acid synthase 2; 5-aminolevulinate synthase 2; 5-aminolevulinate synthase;
5-aminolevulinate synthase 2; Alas 2; ALAS; ALAS E; ALAS, erythroid; ALASE;
Aminolevulinate, delta-, synthase 2; Aminolevulinic acid synthase 2, erythroid;
ANH1; ASB; Delta ALA synthase 2; Delta ALA synthetase; Delta aminolevulinate
synthase 2; Delta aminolevulinate synthase; Erythroid specific ALAS; FLJ93603;
XLDPP; XLSA.
交叉反应 :Human,
Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep
标记 :Unconjugated
抗体来源:Rabbit
抗体类型:Polyclonal
免疫原:KLH
conjugated synthetic peptide derived from human ALAS2/ALAS-E
蛋白细胞定位:细胞浆
纯化方法:affinity
purified by Protein A
亚型:IgG
性状:Liquid
浓度:1mg/ml
储存液:0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件:Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
背景资料5-aminolevulinate synthase 1 (ALAS-H) and 2 (ALAS-E) are two isoforms of ALAS,
an enzyme catalyzing the first step of the heme biosynthetic pathway in
mammals. The erythroid-specific isoenzyme, ALAS-E, regulates the first step of
hematopoietic cell differentation and iron metabolism in the liver. ALAS-H is a
housekeeping protein which mediates synthesis of early heme in the mitochondria
of most cells. Succinyl CoA associates with ALAS-E in protein conformation
change and translocation of ALAS-E into the mitochondria and does not interact
with ALAS-H. The ALAS-E 5'-flanking region contains binding sites for nuclear
activators such as GATA-1, NF-E2 and EKLF. Since the ALAS e maps to the X
chromosome, mutation of the e leads to the pyridoxine-refractory X-linked
sideroblastic anemia.
产物介绍:
5-aminolevulinate synthase 1 (ALAS-H) and 2
(ALAS-E) are two isoforms of ALAS, an enzyme catalyzing the first step of the
heme biosynthetic pathway in mammals. The erythroid-specific isoenzyme,
ALAS-E, regulates the first step of hematopoietic cell differentation and
iron metabolism in the liver. ALAS-H is a housekeeping protein which mediates
synthesis of early heme in the mitochondria of most cells. Succinyl CoA
associates with ALAS-E in protein conformation change and translocation of
ALAS-E into the mitochondria and does not interact with ALAS-H. The ALAS-E
5'-flanking region contains binding sites for nuclear activators such as
GATA-1, NF-E2 and EKLF. Since the ALAS e maps to the X chromosome, mutation
of the e leads to the pyridoxine-refractory X-linked sideroblastic anemia. |
多克隆抗体制备:
我公司合成抗原,保证阳性血清和抗体贰尝滨厂础效价达到1:32000,由蛋白抗原制备的多抗,保证奥叠检测结果是阳性。技术服务实行分步报价,按节点收费,为客户节约成本。
鼠单克隆抗体制备:
客户可根据项目实际需求情况灵活选择进行,我公司将为您的项目提供专业的建议。在制备过程中,与客户互动验证,确保最终制备的抗体贰尝滨厂础阳性血清检测达到合同要求的同时,也能满足客户抗体最终应用验证需求。技术服务实行分步报价,按节点收费,为客户节约成本。
重组抗体表达服务:
重组抗体技术使制备人源化抗体和人源抗体成为可能,而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。我公司已搭建好的抗体测序、重组抗体表达等先进平台,能为客户提供各种类型的重组抗体表达服务,包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达,抗体人源化改造及表达等服务。
单项免疫学及检测服务:
我公司也为客户提供单项免疫学和检测服务,如动物免疫、动物饲养、抗体修饰服务(如贵滨罢颁,贬搁笔等的标记)、以及贰尝滨厂础,奥叠,滨贬颁,顿叠等检测服务。
抗体定制服务:
已注册商标,主要用于抗体药物发现和开发,是我公司针对有特定应用要求和各种模型测试的客户量身定制的专业服务,主要面向工业客户。
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