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内质网Aβ相关结合蛋白抗体
产物名称 | 英文名称 | 货号 |
内质网Aβ相关结合蛋白抗体 | ERAB/HSD17B10 | GOY-01K1532 |
商品属性：
英文名称: ERAB/HSD17B10
中文名:内质网Aβ相关结合蛋白抗体
别 名；HSD17B10;
Mitochondrial L3 Hydroxyacyl CoA Dehydrogenase; 17 beta hydroxysteroid
dehydrogenase 10; 17 beta hydroxysteroid dehydrogenase type 10; 17b HSD10; 3
hydroxy 2 methylbutyryl CoA dehydrogenase; 3 hydroxyacyl CoA dehydrogenase type
2; 3 hydroxyacyl CoA dehydrogenase type II; AB binding alcohol dehydrogenase;
ABAD; Ads9; Amyloid beta binding polypeptide; Amyloid beta peptide binding
alcohol dehydrogenase; Amyloid beta peptide binding protein; CAMR; DUPXp11.22;
Endoplasmic Reticulum Amyloid Binding Protein; Endoplasmic reticulum associated
amyloid beta peptide binding protein; ER associated amyloid beta-binding
protein; ERAB; HADH 2; HADH2; HCD 2; HCD2; HSD17B10; Hydroxyacyl CoA
Dehydrogenase type II; Hydroxyacyl Coenzyme A dehydrogenase type II;
Hydroxysteroid (17 beta) dehydrogenase 10; Mental retardation X linked
syndromic 11; MHBD; Mitochondrial L3 Hydroxyacyl CoA Dehydrogenase;
Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; MRPP2;
MRX17; SCHAD; SDR5C1; Short chain dehydrogenase/reductase family 5C member 1;
Short chain L 3 hydroxyacyl CoA dehydrogenase type 2; Short chain type
dehydrogenase/reductase XH98G2; Type 10 17b HSD; Type 10 17beta hydroxysteroid
dehydrogenase; Type II HADH; XH98G2.
研究领域；免疫学 神经生物学 线粒体
抗体来源；Mouse
克隆类型；Polyclonal
交叉反应； (predicted:
Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, Guinea Pig, )
产物应用；ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理论分子量；21kDa
细胞定位；细胞浆 线粒体
性 状；Liquid
浓 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human ERAB: 51-130/196
亚 型；IgG
纯化方法；affinity
purified by Protein A
缓 冲 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事项；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
产物介绍:
This gene encodes 3-hydroxyacyl-CoA dehydrogenase
type II, a member of the short-chain dehydrogenase/reductase superfamily. The
gene product is a mitochondrial protein that catalyzes the oxidation of a
wide variety of fatty acids, alcohols, and steroids. The protein has been
implicated in the development of Alzheimer's disease, and mutations in the
gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency
(MHBD). Several alternatively spliced transcript variants have been
identified, but the full-length nature of only two transcript variants has
been determined. [provided by RefSeq, Jul 2008]. Functions in mitochondrial tRNA maturation. Part
of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1,
MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their
5'-ends. By interacting with intracellular amyloid-beta, it may contribute to
the neuronal dysfunction associated with Alzheimer disease (AD). |
多克隆抗体制备：
我公司合成抗原，保证阳性血清和抗体贰尝滨厂础效价达到1：32000，由蛋白抗原制备的多抗，保证奥叠检测结果是阳性。技术服务实行分步报价，按节点收费，为客户节约成本。
鼠单克隆抗体制备:
客户可根据项目实际需求情况灵活选择进行，我公司将为您的项目提供专业的建议。在制备过程中，与客户互动验证，确保最终制备的抗体贰尝滨厂础阳性血清检测达到合同要求的同时，也能满足客户抗体最终应用验证需求。技术服务实行分步报价，按节点收费，为客户节约成本。
重组抗体表达服务:
重组抗体技术使制备人源化抗体和人源抗体成为可能，而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。我公司已搭建好的抗体测序、重组抗体表达等先进平台，能为客户提供各种类型的重组抗体表达服务，包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达，抗体人源化改造及表达等服务。
单项免疫学及检测服务:
我公司也为客户提供单项免疫学和检测服务，如动物免疫、动物饲养、抗体修饰服务（如贵滨罢颁，贬搁笔等的标记）、以及贰尝滨厂础，奥叠，滨贬颁，顿叠等检测服务。
抗体定制服务:
已注册商标，主要用于抗体药物发现和开发，是我公司针对有特定应用要求和各种模型测试的客户量身定制的专业服务，主要面向工业客户。
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